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Reflexões sobre a escuta clínico-política de pessoas negras imigrantes na realidade brasileira clínicopolítica clínico política
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Andrade, Paula Campos

; Machado, Gustavo da Silva

; Gomes, Marcela de Andrade

REMHU: Revista Interdisciplinar da Mobilidade Humana

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dec 2023, Volume 31 N. 69 Pages 231 - 247

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste texto é discutir o processo de racialização de imigrantes e refugiados na realidade brasileira à luz de teorias psicanalíticas, sociais-críticas e decoloniais. Como objeto para esta reflexão, partimos da nossa experiência de trabalho clínico-política no atendimento a esta população em diferentes contextos e apoiadas em recortes de diário de campo das autoras. Estabelecemos um diálogo entre a nossa prática e um levantamento bibliográfico que sustenta nosso fazer. Concluímos que o racismo e seus efeitos não devem ser palavras "temidas" no ofício da escuta, ao contrário, devemos combatê-los por meio da produção de espaços críticos de produção simbólica. psicanalíticas sociaiscríticas sociais críticas decoloniais reflexão clínicopolítica clínico política autoras fazer temidas "temidas escuta contrário combatêlos combatê los simbólica

Abstract The purpose of this paper is to discuss the process of racialization of immigrants and refugees in the Brazilian reality in the light of psychoanalytic, social-critical and decolonial theories. As an object for this reflection, we started from our clinical-political work experience in serving this population in different contexts and supported by a field diary of one of the authors. We conclude that racism and its effects should not be "feared" words in the office of listening; on the contrary, we should fight them by giving space to symbolic production. psychoanalytic socialcritical social critical theories reflection clinicalpolitical clinical political authors feared "feared listening contrary production

https://doi.org/10.1590/1980-85852503880006914

Dysarthria in hereditary spastic paraplegia type 4
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Jacinto-Scudeiro, Lais Alves

; Rothe-Neves, Rui

; Santos, Vanessa Brzoskowski dos

; Machado, Gustavo Dariva

; Burguêz, Daniela

; Padovani, Marina Martins Pereira

; Ayres, Annelise

; Rech, Rafaela Soares

; González-Salazar, Carelis

; França Junior, Marcondes Cavalcante

; Saute, Jonas Alex Morales

; Olchik, Maira Rozenfeld

Clinics

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2023, Volume 78 elocation 100128

Abstract: En | Text: En | PDF: En

Abstract Objective: To describe the speech pattern of patients with hereditary Spastic Paraplegia type 4 (SPG4) and correlated it with their clinical data. Methods: Cross-sectional study was carried out in two university hospitals in Brazil. Two groups participated in the study: the case group (n = 28) with a confirmed genetic diagnosis for SPG4 and a control group (n = 17) matched for sex and age. The speech assessment of both groups included: speech task recording, acoustic analysis, and auditory-perceptual analysis. In addition, disease severity was assessed with the Spastic Paraplegia Rating Scale (SPRS). Results: In the auditory-perceptual analysis, 53.5% (n = 15) of individuals with SPG4 were dysarthric, with mild to moderate changes in the subsystems of phonation and articulation. On acoustic analysis, SPG4 subjects’ performances were worse in measurements related to breathing (maximum phonation time) and articulation (speech rate, articulation rate). The articulation variables (speech rate, articulation rate) are related to the age of onset of the first motor symptom. Conclusion: Dysarthria in SPG4 is frequent and mild, and it did not evolve in conjunction with more advanced motor diseases. This data suggest that diagnosed patients should be screened and referred for speech therapy evaluation and those pathophysiological mechanisms of speech involvement may differ from the length-dependent degeneration of the corticospinal tract.

https://doi.org/10.1016/j.clinsp.2022.100128

Desenvolvimento de um purificador de ar com radiação UVC e filtro HEPA no contexto de COVID-19
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Zhang, Julio Min Fei

; Andrade, Alyssa El Chihimi de

; Machado, Felipe Augusto Moraes

; Ghilardi, Larissa Bornia

; Almeida, Barbara Medeiros

; Falararo, Beatriz Vilas Boas Pugliese

; Machado, Gustavo Alves

; Emygdio, Ana Paula Mendes

; Pereira, Guilherme Martins

; Magalhães, Daniel Varela

; Forner-Cordero, Arturo

; Vasconcellos, Pérola de Castro

Engenharia Sanitaria e Ambiental

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nov 2022, Volume 27 N. 6 Pages 1113 - 1122

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A transmissão de infecções respiratórias tem importante impacto na saúde humana, sobretudo no atual contexto da pandemia de COVID-19. Neste trabalho, discute-se um purificador de ar que utiliza radiação ultravioleta-C (UVC) e filtro high efficiency particulate air (HEPA) como mecanismos para descontaminar ambientes internos com baixa circulação de ar. Para avaliar os parâmetros físico-químicos do equipamento e sua ação microbicida, foram determinados a irradiância produzida pela lâmpada, a vazão na entrada e saída do dispositivo, as alterações na concentração de ozônio e o potencial de descontaminação do equipamento para Staphylococcus aureus, Escherichia coli e Candida albicans. A dose total de radiação UVC que o ar recebe ao passar pelo equipamento foi de 801,4 μJ cm-2, o que representaria a inativação de até 80% de Sars-CoV-2 no ar. Além disso, a eficiência de filtração foi reduzida para cerca de 60% com a diminuição do tamanho da partícula para partículas com menos de 1 μm e manteve-se acima de 90% para MP2,5 e MP10. Nos testes microbiológicos, observou-se redução de 99,4, 99,9 e 99,5% para S. aureus, E. coli e C. albicans, respectivamente, em 11 minutos.

ABSTRACT The transmission of respiratory infections has an important role on human health, especially in the current context of the COVID-19 pandemic. In this work, we present the assessment of an air purifier that uses ultraviolet-C (UVC) radiation and a “High Efficiency Particulate Air” (HEPA) filter as mechanisms to decontaminate indoor environments with low air circulation. To assess the physicochemical and microbicidal characteristics of the equipment, the irradiance produced by the lamp, the flow rate at the entrance and exit of the device, possible changes in the ozone concentration and the equipment's decontamination potential for Staphylococcus aureus, Escherichia coli and Candida albicans. The total dose of UVC radiation that the air receives when passing through the equipment was 801.4 μJ cm-2, which would represent an inactivation of up to 80% of SARS-CoV-2 in the air. Furthermore, the filtration efficiency dropped with smaller particle diameter, and reduced to around 60% for particles with less than 1 μm and remained above 90% for PM2.5 and PM10. In microbiological tests, there was a reduction of 99.4%, 99.9% and 99.5% for S aureus, E. coli and C. albicans, respectively, in 11 minutes.

https://doi.org/10.1590/s1413-415220220114

Plantar ulcer as an atypical manifestation of cutaneous leishmaniasis
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Tironi, Fernanda de Carvalho

; Machado, Gustavo Uzeda

; Arruda, Sergio Marcos

; Machado, Paulo Roberto Lima

Anais Brasileiros de Dermatologia

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jun 2021, Volume 96 N. 3 Pages 352 - 354

Abstract: En | Text: En | PDF: En

Abstract Cutaneous leishmaniasis is characterized by ulcers with raised edges and a granular bottom, mainly on the lower limbs. This is a case report of a male patient with an ulcer on the left plantar region. The diagnosis was confirmed by positive PCR for L. braziliensis and the presence of amastigotes of Leishmania sp. in the histopathological examination. After treatment with Glucantime, the patient showed full healing of the ulcer. The unusual location of the ulceration calls attention to atypical presentations of leishmaniasis, and the importance of histopathological examination and PCR, leading to the appropriate diagnosis and treatment.

https://doi.org/10.1016/j.abd.2020.06.015 61 downloads

Uma abordagem integral para Saneamento Ecológico em Comunidades Tradicionais e Rurais
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Machado, Gustavo Carvalhaes Xavier Martins Pontual

; Maciel, Tania Maria de Freitas Barros

; Thiollent, Michel

Ciência & Saúde Coletiva

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apr 2021, Volume 26 N. 4 Pages 1333 - 1344

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Este artigo apresenta uma abordagem integral para atuar em projetos comunitários, baseada nas três ecologias de Guattari e do seu diálogo com teóricos da psicossociologia, por envolver a necessidade de conjugar intervenções tecnológicas com abordagens sociais. Explora-se essas contribuições para apontar a necessidade do diálogo na implementação de ações de saneamento, principalmente na zona rural e em Comunidades Tradicionais, envolvendo o indivíduo, os grupos atendidos e sua cultura territorial. A abordagem apresentada foi implementada em uma pequisa-ação, junto com a Comunidade Caiçara da Praia do Sono e o Fórum de Comunidades Tradicionais de Angra dos Reis, Paraty e Ubatuba (FCT), a partir do projeto Observatório de Territórios Sustentáveis e Saudáveis da Bocaina (OTSS/Fiocruz). Pode-se constatar que a inclusão dos atores na mobilização social para o saneamento pode estabelecer uma participação social efetiva, que gere tanto uma mudança subjetiva na consciência dos diversos atores locais, como ganhos estruturais que promovam saúde e qualidade de vida. O panorama abordado mostra a importância de uma compreensão global do problema, mas também, simultaneamente, uma atuação local, territorializada, adaptada a cada realidade por meio do diálogo genuíno e uma participação horizontal.

Abstract This article presents an integral approach to work in community projects, based on Guattari’s three ecologies and its dialogue with psychosocial theorists, since it involves the need to combine technological interventions with social approaches. These contributions are explored to point out the need for dialogue in the implementation of sanitation actions, mainly in the rural area and in traditional communities, involving the individual, the groups served and their territorial culture. The approach presented was implemented in a joint action with the Caiçara Community of Praia do Sono and the Forum of Traditional Communities of Angra dos Reis, Paraty and Ubatuba (FCT), based on the Observatory of Sustainable and Healthy Territories of Bocaina (OTSS / Fiocruz). It could be verified that the inclusion of the actors in the social mobilization for the sanitation can entail an effective social participation that generates both a subjective change in the conscience of the diverse local actors and structural gains that promote health and quality of life. The panorama covered shows the importance of a global understanding of the problem, but also, of a simultaneous local, territorialized action, adapted to each reality through genuine dialogue and horizontal participation.

https://doi.org/10.1590/1413-81232021264.08242019 735 downloads

Effects of photobiomodulation therapy on functional recovery, angiogenesis and redox status in denervated muscle of rats
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Nascimento, Jéssica Junia Aparecida Cardoso

; Machado, Alex Sander Dias

; Della-Santa, Giovanna Moura Lamas

; Fernandes, Danielle Cristina

; Ferreira, Marcílio Coelho

; Machado, Gustavo Augusto Pereira

; Chaves, Bruna Carolina Garcia

; Costa, Karine Beatriz

; Rocha-Vieira, Etel

; Oliveira, Murilo Xavier

; Gaiad, Thais Peixoto

; Santos, Ana Paula

einstein (São Paulo)

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2021, Volume 19 elocation eAO6001

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar os efeitos da terapia de fotobiomodulação no estado redox, no marcador de angiogênese – fator de crescimento endotelial vascular – e na recuperação funcional do músculo desnervado. Métodos: Um total de 32 ratas Wistar foi submetido a uma lesão por esmagamento e dividido aleatoriamente em quatro grupos: Grupo Diodo Emissor de Luz 2 e Grupo Controle 2 (músculo coletado 2 dias após a lesão), além do Grupo Diodo Emissor de Luz 21 e do Grupo Controle 21 (músculo coletado 21 dias após a lesão). Grupo Diodo Emissor de Luz 2 e Grupo Diodo Emissor de Luz 21 receberam duas e dez aplicações de diodo emissor de luz (630±20nm, 9J/cm2e 300mW), respectivamente, e Grupo Controle 2 e Grupo Controle 21 não receberam tratamento. A função foi avaliada pelo teste de preensão em quatro momentos (pré-lesão, 2, 10 e 21 dias após a lesão). O músculo flexor dos dedos foi coletado para análise dos parâmetros redox e da imunolocalização do fator de crescimento endotelial vascular. Resultados: Houve melhora funcional no segundo e décimo dia pós-lesão nos grupos tratados em comparação aos controles (p<0,005). O tecido muscular dos grupos tratados apresentou maior expressão imuno-histoquímica do fator de crescimento endotelial vascular. A terapia de fotobiomodulação diminuiu o dano oxidativo aos lipídeos no Grupo Diodo Emissor de Luz 2 comparado ao Grupo Controle 2 (p=0,023) no músculo desnervado. Conclusão: A terapia de fotobiomodulação acelerou a recuperação funcional, aumentou a angiogênese e reduziu a peroxidação lipídica no músculo desnervado 2 dias após a lesão.

ABSTRACT Objective: To evaluate the effects of photobiomodulation therapy in redox status, angiogenesis marker – vascular endothelial growth factor – and in the functional recovery in denervated muscle. Methods: A total of 32 female Wistar rats underwent a crush injury and were randomly divided into four groups: Light Emitting Diode Group 2 and Control Group 2 (muscle collected 2 days after injury), and Light Emitting Diode Group 21 and Control Group 21 (muscle collected 21 days afterinjury). Light Emitting Diode Group 2 and Light Emitting Diode Group 21 received two and ten light emitting diode applications (630±20nm, 9J/cm2, 300mW), respectively, and the Control Group 2 and Control Group 21 did not receive any treatment. The function was evaluated by grasping test at four moments (pre-injury, 2, 10 and 21 post-injury days). The flexor digitorum muscle was collected for analysis of immunolocalization of vascular endothelial growth factor and redox parameters. Results: Functional improvement was observed at the second and tenth post-injury day in treated groups compared to control (p<0.005). The muscle tissue of treated groups presented higher immunohistochemical expression of vascular endothelial growth factor. Photobiomodulation therapy decreased the oxidative damage to lipid in Light Emitting Diode Group 2 compared to Control Group 2 (p=0.023) in the denervated muscle. Conclusion: Photobiomodulation therapy accelerated the functional recovery, increased angiogenesis and reduced lipid peroxidation in the denervated muscle at 2 days after injury.

https://doi.org/10.31744/einstein_journal/2021ao6001 66 downloads

O comum e os desdobramentos na economia solidária a partir do saneamento ecológico
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Machado, Gustavo Carvalhaes Xavier Martins Pontual

; Maciel, Tania Maria de Freitas Barros

; Thiollent, Michel Jean Marie

Saúde e Sociedade

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2021, Volume 30 N. 1 elocation e181188

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Como as condições de saneamento no Brasil são precárias nas áreas rurais, é importante construir ações territorializadas que valorizem a cultura e fortaleçam o bem viver, baseadas na economia solidária para alcançar soluções sustentáveis. Dardot e Laval veem o comum como um contraponto ao atual contexto político e econômico, em que os indivíduos assumem o papel de protagonistas em suas vidas e gerenciam os “comuns” para a comunidade da qual fazem parte. Partindo dessa abordagem, a Fundação Osvaldo Cruz (Fiocruz), por meio do Observatório dos Territórios Saudáveis e Sustentáveis de Bocaina (OTSS), constituiu pesquisa-ação de saneamento ecológico na Comunidade Caiçara da Praia do Sono, em Paraty, com envolvimento da comunidade durante todo o processo e, por meio de avaliação qualitativa, pôde-se entender a relação da comunidade com o comum. Como os construtores locais foram contratados como mobilizadores sociais, os recursos endógenos foram valorizados. Por meio dessa articulação, buscou-se a atuação conjunta junto aos órgãos públicos para fomentar ações que partissem da própria comunidade e políticas públicas inclusivas que colocam a sociedade como protagonista do processo. A partir do conceito de comum e de entrevistas semiestruturadas, esta pesquisa psicossocial tem como objetivo relatar o desdobramento da economia solidária no comum.

Abstract As sanitation conditions in Brazil are precarious in rural areas, it is important to build territorial actions that value culture and strengthen good living based on solidarity economy to achieve sustainable solutions. Dardot and Laval see the “common” as a counterpoint to the current political and economic context, in which individuals assume the role of protagonists in their lives and manage the “commonalities” for their community. In this approach, the Oswaldo Cruz Foundation (Fiocruz), through the Observatory of Sustainable and Healthy Territories of Bocaina (OTSS), constituted an ecological sanitation research in the Caiçara Community of Praia do Sono, in Paraty, with the participation of the community during the whole process and, through a qualitative evaluation, the relationship between the community and the common could be understood. Local builders were hired as social mobilizers, thus valuing endogenous resources. Through this articulation, joint action with public agencies was sought to foster actions that came from the community itself and inclusive public policies that put a society at the center of the process. Supported by the concept of common and by semi-structured interviews, this psychosocial study examines the unfolding of the solidarity economy.

https://doi.org/10.1590/s0104-12902021181188 366 downloads

O comum e os desdobramentos na economia solidária a partir do saneamento ecológico
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Machado, Gustavo Carvalhaes Xavier Martins Pontual

; Maciel, Tania Maria de Freitas Barros

; Thiollent, Michel Jean Marie

Saúde e Sociedade

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2021, Volume 30 N. 1 elocation e181188

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/s0104-12902021181188

Uma abordagem integral para Saneamento Ecológico em Comunidades Tradicionais e Rurais
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Machado, Gustavo Carvalhaes Xavier Martins Pontual

; Maciel, Tania Maria de Freitas Barros

; Thiollent, Michel

Ciência & Saúde Coletiva

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2021, Volume 26 N. 4 Pages 1333 - 1344

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232021264.08242019

10.

COMVC-19: A Program to protect healthcare workers’ mental health during the COVID-19 Pandemic. What we have learned
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Fukuti, Pedro

; Uchôa, Caroline Louise Mesquita

; Mazzoco, Marina Flaborea

; Cruz, Isabella D'Andrea Garcia da

; Echegaray, Mariana V.F.

; Humes, Eduardo de Castro

; Silveira, Júlia Belizário

; Santi, Talita Di

; Miguel, Euripedes Constantino

; Corchs, Felipe

; Fatori, Daniel

; Campello, Guilherme

; Oliveira, Gabriel M. de

; Argolo, Felipe C.

; Ferreira, Felipe de M.

; Machado, Gustavo

; Argeu, Adriana

; Oliveira, Graça Maria Ramos de

; Serafim, Antônio de Pádua

; Siqueira, Luciana de Lima

; Rossi, Luciane de

; Rios, Izabel Cristina

; Oliveira, Talita Rodrigues de

; Antoniazzi, Leilane C. K.

; Gagliotti, Daniel Augusto Mori

; Abelama Neto, Emílio

; Oliveira Junior, Paulo Novais de

; Correia, Aline Villalobo

; Gonçalves, Luca Schilling

; Tortato, Liana Silva

; Busato, Wagner Machado Moraes

; Guimarães-Fernandes, Flávio

; Alves, Marcos

; Leite Netto, Oswaldo Ferreira

; Schoueri, Patrícia de Campos Lindenberg

; Roque, Márcio de Assis

; Merlin, Silvia Stahl

; Boer, Giovana Cardoso Machado

; Sallet, Paulo Clemente

; Malbergier, André

; Spedo, Mariana Abrahão

; Kamitsuji, Carla Satie

; Faria, Elizabeth de

; Moreira, Moacyr Vergara de Godoy

; Kaufman, Arthur

; Abdo, Carmita

; Scanavino, Marco de Tubino

; Lancman, Selma

; Tavares, Hermano

; Polanczyk, Guilherme

; Brunoni, André R.

; Forlenza, Orestes V.

; Barros-Filho, Tarcísio Eloy Pessoa de

Clinics

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2021, Volume 76 elocation e2631

Abstract: En | Text: En | PDF: En

OBJECTIVE: In 2020, the COVID-19 pandemic brought a work and stress overload to healthcare workers, increasing their vulnerability to mental health impairments. In response, the authors created the COMVC-19 program. The program offered preventive actions and mental health treatment for the 22,000 workers of The Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). This paper aims to describe its implementation and share what we have learned from this experience. METHODS: Workers were able to easily access the program through a 24/7 hotline. Additionally, a mobile phone app that screened for signs and symptoms of emotional distress and offered psychoeducation and/or referral to treatment was made available. Data from both these sources as well as any subsequent psychiatric evaluations were collected. RESULTS: The first 20 weeks of our project revealed that most participants were female, and part of the nursing staff working directly with COVID-19 patients. The most frequently reported symptoms were: anxiety, depression and sleep disturbances. The most common diagnoses were Adjustment, Anxiety, and Mood disorders. CONCLUSIONS: Implementing a mental health program in a multimodal intervention was feasible in a major quaternary public hospital. Our data also suggests that preventive actions should primarily be aimed at anxiety and depression symptoms, with a particular focus on the nursing staff.

https://doi.org/10.6061/clinics/2021/e2631

11.

Distribution and composition of Dragonfly and Damselfly species (Odonata) of the upper Rio das Velhas, Ouro Preto, Minas Gerais State, Brazil
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Ávila Júnior, Walter Francisco de

; Machado, Gustavo Lisboa Vieira

; Lencioni, Frederico Augusto de Atayde

; Carneiro, Marco Antônio Alves

Papéis Avulsos de Zoologia

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2020, Volume 60 elocation e20206065

Abstract: En | Text: En | PDF: En

Abstract This paper describes the composition and distribution of Anisoptera and Zygoptera (Odonata) species of the upper Rio das Velhas in the municipality of Ouro Preto, Minas Gerais State, Brazil. A total of 727 specimens of 40 species were collected near water bodies over a period of 23 months between 2015 and 2017. The families with greatest species richness were Libellulidae (13 species), Coenagrionidae (12 species) and Heteragrionidae and Aeshnidae (4 species each). Notable among the species collected were Perilestes fragilis Hagen in Selys, 1862, inhabiting well-preserved forests, Minagrion waltheri Santos, 1965, pertaining a endemic genus of Brazil and the recently described Heteragrion caueiÁvila-Júnior et al., 2017, and three species recorded for the first time for the state: Elasmothemis alcebiadesi (Santos, 1945), Erythrodiplax melanica Borror, 1942 and Erythrodiplax acantha Borror, 1942, the latter is considered Critically Endangered (CR) by the International Union for Conservation of Nature's (IUCN) Red List.

https://doi.org/10.11606/1807-0205/2020.60.65 136 downloads

12.

Prevalence of oropharyngeal dysphagia in hereditary spastic paraplegias
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Jacinto-Scudeiro, Laís Alves

; Machado, Gustavo Dariva

; Ayres, Annelise

; Burguêz, Daniela

; Polese-Bonatto, Marcia

; González-Salazar, Carelis

; Siebert, Marina

; França Junior, Marcondes Cavalcante

; Olchik, Maira Rozenfeld

; Saute, Jonas Alex Morales

Arquivos de Neuro-Psiquiatria

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dec 2019, Volume 77 N. 12 Pages 843 - 847

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO As paraparesias espásticas hereditárias (PEH) são um grupo de doenças genéticas caracterizado por espasticidade dos membros inferiores com ou sem características neurológicas adicionais. A disfunção da deglutição é pouco estudada nas PEH e sua presença pode levar a complicações respiratórias e nutricionais significativas. Objetivo: O objetivo deste estudo foi avaliar a frequência e a caracterização clínica da disfagia em diferentes tipos de PEH. Métodos: Foi realizado um estudo transversal em dois centros. Os pacientes com PEH confirmados geneticamente foram avaliados pelo Northwestern Dysphagia Patient Check Sheet e pela Escala Funcional de Ingestão Oral. Além disso, a autopercepção da disfagia foi avaliada pelo Eat Assessment Tool-10 e pelo Swallowing Disturbance Questionnaire. Resultados: Trinta e seis pacientes com paraplegia espástica tipo 4 (SPG4), cinco com SPG11, quatro com SPG5, quatro com xantomatose cerebrotendinosa (CTX), três com SPG7 e dois com SPG3A foram avaliados. Disfagia orofaríngea leve a moderada estava presente em 3/5 (60%) dos pacientes com SPG11 e 2/4 (50%) dos pacientes com CTX. Um único SPG4 (2%) e um único SPG7 (33%) apresentaram disfagia orofaríngea leve. Todos os outros pacientes avaliados apresentaram deglutição normal ou funcional. Conclusão: Disfagia orofaríngea clinicamente significativa estava presente apenas nas formas complicadas de PEH. A SPG11 e CTX apresentaram maiores riscos de disfagia, sugerindo que a avaliação da deglutição deve fazer parte do manejo dos pacientes com essas condições.

ABSTRACT Hereditary spastic paraplegias (HSP) are a group of genetic diseases characterized by lower limb spasticity with or without additional neurological features. Swallowing dysfunction is poorly studied in HSP and its presence can lead to significant respiratory and nutritional complications. Objectives: The aim of this study was to evaluate the frequency and clinical characteristics of dysphagia in different types of HSP. Methods: A two-center cross-sectional prevalence study was performed. Genetically confirmed HSP patients were evaluated using the Northwestern Dysphagia Patient Check Sheet and the Functional Oral Intake Scale. In addition, self-perception of dysphagia was assessed by the Eat Assessment Tool-10 and the Swallowing Disturbance Questionnaire. Results: Thirty-six patients with spastic paraplegia type 4 (SPG4), five with SPG11, four with SPG5, four with cerebrotendinous xanthomatosis (CTX), three with SPG7, and two with SPG3A were evaluated. Mild to moderate oropharyngeal dysphagia was present in 3/5 (60%) of SPG11 and 2/4 (50%) of CTX patients. A single SPG4 (2%) and a single SPG7 (33%) patient had mild oropharyngeal dysphagia. All other evaluated patients presented with normal or functional swallowing. Conclusions: Clinically significant oropharyngeal dysphagia was only present in complicated forms of HSP Patients with SPG11 and CTX had the highest risks for dysphagia, suggesting that surveillance of swallowing function should be part of the management of patients with these disorders.

https://doi.org/10.1590/0004-282x20190180 1280 downloads

13.

A escuta psicológica como ferramenta de integração: práticas clínicas e sociais em um Centro de Referência de Atendimento a Imigrantes em Santa Catarina
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Machado, Gustavo da Silva

; Barros, Allyne Fernandes Oliveira

; Martins Borges, Lucienne

REMHU: Revista Interdisciplinar da Mobilidade Humana

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apr 2019, Volume 27 N. 55 Pages 79 - 96

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As migrações representam modificações nos territórios geográfico e subjetivo que precisam de acolhida e suporte para manutenção do fio de condução entre o sujeito que migra e sua própria história. Este artigo apresenta reflexões sobre a construção de um Serviço de Psicologia dentro de um Centro de Referência de Atendimento a Imigrantes, em Santa Catarina, na cidade de Florianópolis, e a utilização da escuta psicológica como ferramenta na qualificação da acolhida e integração de imigrantes e refugiados nesta região.

Abstract Migrations represent changes in the geographic and subjective territories that need to be received and supported, looking for the maintenance of the conduction between the migrating subject and their own history. This article shows reflections on the construction of a Psychology Service within a Reference Center for Assistance to Immigrants, in Santa Catarina, in the city of Florianópolis, and the use of psychological care as a tool in qualifying the reception and integration of immigrants and refugees in this region.

https://doi.org/10.1590/1980-85852503880005506 3771 downloads

14.

Disseminated leishmaniasis: clinical, pathogenic, and therapeutic aspects
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Machado, Gustavo Uzêda

; Prates, Fernanda Ventin

; Machado, Paulo Roberto Lima

Anais Brasileiros de Dermatologia

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feb 2019, Volume 94 N. 1 Pages 9 - 16

Abstract: En | Text: En | PDF: En

Abstract: Disseminated leishmaniasis is a severe and emerging form of American tegumentary leishmaniasis. Disseminated leishmaniasis is defined by the presence of more than 10 polymorphic cutaneous lesions, distributed over more than two noncontiguous parts of the body. Nasal mucosal involvement is observed in almost half of cases. Disseminated leishmaniasis patients present with a decreased production of Th1 cytokines in the peripheral blood due to the attraction of leishmania- activated T cells to the multiple cutaneous lesions. Disseminated leishmaniasis development is poorly understood and is related to a complex network involving environmental, host immune response, and parasite factors, in which L. braziliensis polymorphism plays an important role. Disseminated leishmaniasis is a challenging disease to cure, presenting a high failure rate of 75% to pentavalent antimony therapy. Despite its importance and severity, this form of American tegumentary leishmaniasis has been poorly studied and documented, deserving greater attention from professionals working in endemic areas.

https://doi.org/10.1590/abd1806-4841.20198775 1739 downloads

15.

Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period
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SANTOS, DAIANE S. DOS

; BOITO, JHONATAN P.

; KLAUCK, VANDERLEI

; REIS, JOÃO H. DOS

; GEBERT, ROGER R.

; GLOMBOWSKY, PATRÍCIA

; BIAZUS, ANGELISA H.

; BOTTARI, NATHIELI B.

; SOUSA, REJANE S.

; MACHADO, GUSTAVO

; LEAL, MARTA L.R.

; BALDISSERA, MATHEUS D.

; BERWANGER, JEAN C.

; SILVA, ALEKSANDRO S. DA

Anais da Academia Brasileira de Ciências

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2019, Volume 91 N. 1 elocation e20171042

Abstract: En | Text: En | PDF: En

Abstract: The aims of this study were to investigate whether treatments with zinc edetate (Zn) and diphenyl diselenide ((PhSe)2) enhance performance, immune responses, protein metabolism, and oxidant/antioxidant status in calf serum and muscle. Animals were divided into four groups (n=6 each): control (without supplementation), and groups supplemented on days 50 and 70 of life with (PhSe)2, Zn, and a combination of (PhSe)2 and Zn. Animals treated with (PhSe)2 gained more weight by experimental day 220 than did the control group, but there was no difference by the end of the experiment (day 300). The absolute number of leukocytes and lymphocytes increased in groups Zn and (PhSe)2+Zn on day 20 of experiment, but decreased on day 40 in groups (PhSe)2, and (PhSe)2+Zn. The number of monocytes decreased in all groups compared with control. One of the principal findings was that (PhSe)2+Zn together had beneficial effects on protein metabolism, represented by increases total protein and globulin levels, compared with the control group. The combination of (PhSe)2 and Zn led to low levels of TBARS and ROS in serum and muscle, and stimulated antioxidant enzyme activities. Thus, supplementation with (PhSe)2+Zn may be a compelling approach to augmenting the calf antioxidant system during weaning.

https://doi.org/10.1590/0001-3765201920171042 1416 downloads

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